Vitalzym Systemic Enzymes
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The World's First and Only Stem Cell Enhancer

The New & Improved
ystemic Enzymes 
In New Enteric Coated Liquid Filled Veggie Gel Caps

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One way to describe the function of systemic enzymes would be to say it helps to turn back the clock. Vitalzym systemic proteolytic enzyme therapy assists the body by 

Why Systemic Enzymes
Vitalzym is a blend of enzymes that work synergistically to provide total system support. It contains protease, serrapeptase, papain, bromelain, amylase, lipase, rutin and amla. Enzymes are the building blocks of life. Enzymes are the biocatalysts necessary for the chemical reactions associated with breathing, growth, reproduction, digestion and all other metabolic functions. For most people under the age of 25, enzymes are efficiently produced by the body to maintain optimal health. As we age, our levels of enzyme production begin to decelerate. This reduction of enzyme levels may cause our bodies and normal body functions to break down.*

Supplementation with systemic enzymes may help the body to more efficiently use its own metabolic enzymes, thereby reducing the physiological effects of aging. Vitalzym is a unique blend of powerful systemic enzymes that may help the body to more efficiently use its own metabolic enzymes.*

Physicians in Europe and Asia have long prescribed systemic enzyme supplements to restore enzyme levels and promote natural healing. Combined with professional healthcare, proper diet and exercise, Vitalzym may help you to maintain proper enzyme amounts and balance your body's own repair mechanisms.*

Vitalzym Systemic Enzyme Therapy for Healthier Bodies

Vitalzym systemic enzymes and systemic enzyme therapy are needed for each biochemical reaction that takes place and makes life possible. Enzymes initiate millions of reactions within your body. Without enzymes, life could not exist. "Systemic" means whole-body therapy, not just a digestive therapy.

Additionally, systemic enzymes are the foundation that makes all of your other vitamin supplements work properly. As a biocatalyst, enzymes help to drive multiple reactions throughout the body. We have roughly 3,000 enzymes in our bodies, and over 7,000 enzymic reactions.

Systemic enzymes promote healthier bodies and wellness. As we age, our body's natural production of enzymes slows or stops. Supplementation of enzymes with Vitalzym, along with proper diet and exercise, will help to maintain your normal enzyme levels, balancing your body's own repair mechanisms and increasing your health and wellness.

New Enteric Coated Liquid Gel Vitalzym

Enteric Coating - The effectiveness of any systemic enzyme is determined by the amount of activity level in the brood stream (in vivo) after being absorbed from small intestine. Enzymes, whose activities are significantly lost in an acidic environment, must be protected for their utmost effectiveness. Enzymes will begin to lose their activity once introduced into the low pH (1.0 - 3.0) acids of the stomach. The amount of activity loss is dependent upon the individual enzyme and the amount of time in the stomach. Studies have shown that unprotected enzymes can lose up to 100% of their activity in fewer than 30 minutes in pH levels below 3.0. The only method to ensure that 100% of the ingredients are not destroyed by the stomach acids is to enteric coat the enzymes. Vitalzym has been reformulated to use a pharmaceutical grade enteric coated gel capsule.

The new enteric coated gel capsule has been designed to pass both the USP (United States Pharmacopeia) and JP (Japan Pharmacopeia) disintegration tests for enteric coated capsules. Every production batch is tested to meet the agency guidelines before exportation to the US. Though revolutionary to nutritional enzyme blends, this enteric coating process is similar to those used in today's most advanced pharmaceuticals. The capsule has a corn protein shell barrier that allows it to withstand the extremely low pH levels found in the stomach. Once introduced to the pancreatic juices in the duodenum (upper small intestine), the shell barrier breaks down to release its enzymes. The enzymes are then absorbed into the blood stream through the lining of the small intestine. The corn protein barrier is the same as that used by the Japanese pharmaceutical blend of serrapeptase. (Dasen, Takeda Pharmaceutical Company Limited)

The new enteric coated gel capsule has been designed to pass both the USP (United States Pharmacopeia) and JP (Japan Pharmacopeia) disintegration tests for enteric coated capsules. Every production batch is tested to meet the agency guidelines before exportation to the US.

Solubilized Liquid Filled Gel Capsule - At the center of the advanced delivery system is a new Solubilized Liquid Filled Gel Capsule. The technology of liquid enzymes is superior to that of capsules filled with powder due to low heat production, more uniform dose distribution and prolonged enzyme activity.

Low Heat Production - Enzyme blends are available today that use an enteric coating, however they are in tablet form. The disadvantage of these blends is the amount of heat created when compressing the ingredients in to a tablet. Enzymes are susceptible to high temperatures and may begin to degrade during the manufacturing process. Solubilized Liquid Filled Capsules allow for an enteric coated enzyme without activity loss from heat. Throughout all of the processes,
Vitalzym is produced under strictly controlled temperature ranges.

Optimal Distribution - Liquid enzymes are able to provide a more uniform dose consistency because the mixing of liquids allows for optimal particle distribution. In powder formulations, each particle of a different enzyme is different in size, causing greater friction between particles when mixing. Excipients are introduced to powder formulations to help increase the mixability, however liquids still prove to be far more evenly distributed allowing for more consistent dosages in each capsule.

Prolonged Enzyme Activity - Enzyme blends retain moisture from water when they are produced. When tested using the industry standard "loss on drying" measurement, these blends typically have a 5-10% moisture content. Powder enzyme blends will lose activity as this moisture dries, resulting in a loss of up to 20% of activity over a 12 month period. Vitalzym uses enzymes with higher purity and less moisture that are combined with Medium-Chain Triglycerides (MCT).
The process of combining with the MCT's causes the moisture to separate from the enzyme blend so that it can be removed before encapsulation. As a result, there is no loss of enzyme activity after production due to moisture drying. Users will also experience the many health benefits of MCT's. Vitalzym has been reformulated with a technologically advanced delivery system that allows for reduced dosage and vastly increased effectiveness


Vitalzym is registered as an export medicine, and thus regulated by the Pharmaceutical and Food Safety Bureau under the Ministry of Health, Labor and Welfare in Japan. This agency is the Japanese counterpart of the FDA of the United States Department of Health and Human Services. Since Vitalzym is regulated as a pharmaceutical in Japan, it must adhere to manufacturing requirements that are far more stringent than dietary supplements manufactured in the United States. Supplements manufactured in the United States are considered food grade, and thus, not regulated as pharmaceuticals.

Quality control requirements of a licensed pharmaceutical facility are considered the most hygienic of any industry. Extreme measures are taken to avoid any possibility of contamination. Precautions include clean rooms, dust particle control, and sophisticated air filtration systems. All laboratory equipment and safety measures are inspected by the government during frequent site facility inspections. Each inspection must be passed in order to retain the export licensure.

World Nutrition is also required to notify the Japanese Pharmaceutical and Food Safety Bureau of any variance to the registered ingredient blend. Any blend change would require a new registration for export. Every batch of product must be inspected before and after mixing to test adherence to the registered blend. In addition, every lot of raw materials received by our manufacturing facility must be tested independently of the supplier for safety, impurities, potency, and accuracy. These records must be disclosed upon facility inspections.

These pharmaceutical guidelines unique to Vitalzym ensure each and every capsule is of the utmost purity, potency, and safety.

Vitalzym is protected by a recyclable aluminum can.

Major Functions of Systemic Enzyme Therapy

The following are reported benefits from systemic enzymes, including blends with large quantities of protein eating (proteolytic) enzymes, which Vitalzym contains. Vitalzym contains the most powerful proteolytic enzyme, Serrapeptase.

Fights Inflammation:

  • An anti-inflammatory alternative to over-the-counter pain killers

  • Reduces liver toxins

  • Reduces joint and muscle inflammation

  • Lowers inflammation by removing toxins and debris in the circulatory system

  • Increases penile functionality

  • Reduces the effects of Sjogren's syndrome or disease

Fights Fibrosis:

  • Fights the aging process by removal of fibrin buildup

  • Reduces Fibromyalgia by reduction and removal of fibrin buildup

  • Reduces Endometriosis by removal of fibrin buildup

  • Reduces Uterine Fibroid Tumors by removal of fibrin buildup

  • Reduces Pulmonary Fibrosis by removal of fibrin buildup

  • Reduces Chronic Fatigue Syndrome

  • Reduces thickening of the blood (fibrin deposits), increasing circulation

  • Helps unclog the microcirculation system, increasing circulation

  • Reduces spider veins and wrinkles

  • Reduces formation of scar tissue

  • Reduces post-operative scar tissue, increases healing capabilities

Immune System Modulation:

  • Works to balance the entire body synergy

  • Helps prevent the rejection of transplanted and health-restoring organs and tissues

  • Helps modulate the cell-signaling pathway that triggers immune activation

Fights Blood Contamination:

  • Reduces clogging of the microcirculation system

  • Improves detoxification of the blood

  • Improves the condition of white blood cells

  • Improves the absorption of vitamin and mineral supplements

  • Improves homeostasis

Fights Viruses:

  • Helps internal filters clean the circulation system

  • Improves anti-virals, kills the virus

  • Lowers viral loading


New Enteric Coated Liquid Gel Vitalzym Enzyme

International Shipping Information

Vitalzym Systemic Enzyme 180 gel caps $89.95

Vitalzym Systemic Enzyme 360 gel caps $149.95

  Shipping is FREE in the USA for orders over $100.00 

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Systemic Enzyme Explained by Landis Revin
Systemic Enzymes By William Wong N.D., Ph.D.

Systemic Enzymes

What are Systemic Enzymes and What Do They Do?
By: William Wong N.D., Ph.D. Member World Sports Medicine Hall of Fame The word systemic means body wide.

Systemic enzymes are those that operate, not just for digestion, but throughout your body in every system and organ. But let's take first things first, what is an enzyme? An enzyme is a biocatalyst - something that makes something else work or work faster. Chemical reactions are generally slow things, enzymes speed them up. Without enzymes, the chemical reactions that make up our life would be too slow for life as we know it. (As slow as sap running down a tree in winter). For life to manifest, as we know it, enzymes are essential to speed up the reactions. We have roughly 3000 enzymes in our bodies and over 7000 enzymic reactions. Most of these enzymes are derived or created from what we think of as the protein digesting enzymes. But while digestion is an important part of what enzymes do, it's almost the absolute last function. First and foremost, these body-wide protein-eating enzymes have the following actions:

Natural Anti-Inflammatory Enzymes are the first line of defense against inflammation. (1,2,3). Inflammation is a reaction by the immune system to an irritation. Let's say you have an injured right knee. The immune system, sensing the irritation in the knee, creates a protein chain called a Circulating Immune Complex (CIC for short), tagged specifically for that right knee. (A scientist who found the tagging mechanism won the Nobel Prize in biology in 1999). This CIC floats down to the right knee and causes pain, redness and swelling - the classic earmarks for inflammation. This, at first, is a beneficial reaction; it warns us that a part of ourselves is hurt and needs attention. But, inflammation is self-perpetuating, it creates an irritation that in response, the body makes CIC's for! Aspirin, Ibuprofen, Celebrex, Viox and the rest of the Non Steroidial Anti Inflammatory Drugs all work by keeping the body from making all the CIC's. This ignores the fact that some CIC's are vital to life, like those that maintain the lining of the intestine and those that keep the kidneys functioning! Not to mention the fact that they, along with acetaminophen, are highly toxic to the liver. Every year 20,000 Americans die from these over the counter drugs and another 100,000 will wind up in the hospital with liver damage, kidney damage or bleeding intestines from the side effects of these drugs. (4,5). Systemic enzymes, on the other hand, are perfectly safe and free of dangerous side effects. They have no LD-50, or toxic dose. (6). Best of all, systemic enzymes can tell the difference between the good CIC's and the bad ones. This is due to the fact that hydrolytic enzymes are lock and key mechanisms and their "teeth" will only fit over the bad CIC's. So instead of preventing the creation of all CIC's, systemic enzymes just "eat" the bad ones and in so doing, lower inflammation everywhere. With that, pain is also lowered.

Anti Fibrosis
Enzymes eat scar tissue and fibrosis. (7). Fibrosis is scar tissue and most doctors learn in anatomy that it is fibrosis that eventually kills us all. Let me explain. As we age, which starts at 27, we have a diminishing of the body's output of enzymes. This is because we make a finite amount of enzymes in a lifetime and we use up a good deal of them by the time we reach our 40's (Cystic Fibrosis patients who have virtually no enzyme production to speak of, even as children usually don't make it past their 20's before they die of the restriction and shrinkage in the lungs from the formation of fibrosis or scar tissue).

So our body begins to dole out our enzymes with an eyedropper instead of with a tablespoon. Result: the repair mechanism of the body goes off balance and has nothing to reduce the over abundance of fibrin it deposits in nearly everything from simple cuts, to the inside of our internal organs and blood vessels. It is then when most women begin to develop things like fibrocystic breast disease, uterine fibroids, and endometriosis. We all grow arterial sclerotic (meaning scar tissue) plaque, and have fibrin begin to spider web its way inside of our internal organs, reducing their size and function over time. This is why as we age our wounds heal with thicker, less pliable, weaker and very visible scars.

If we replace the lost enzymes, we can control and reduce the amount of scar tissue and fibrosis our bodies have. As physicians in the US are now discovering, even old scar tissue can be "eaten away" from surgical wounds, pulmonary fibrosis, and kidney fibrosis even keloid years after their formation. Medical doctors in Europe and Asia have known this and used orally administered enzymes for such for over 40 years!

Blood Cleansing
The blood is not only the river of life; it is also the river through which the cells and organs dispose of their waste. Enzymes improve circulation by eating the excess fibrin that causes blood to sometimes get as thick as catsup or yogurt, creating the perfect environment for the formation of clots. All of this material is supposed to be cleaned off by the liver on "first pass" or the first time it goes through. Given the sluggish and near toxic or toxic states of everyone's liver these days, that seldom happens. So the waste remains in the blood, waiting for the liver to have enough free working space and enough enzymes to clean it. This can take days or in some people, weeks! (8).
When systemic enzymes are taken, they stand ready in the blood and take the strain off of the liver by:
Cleaning excess fibrin from the blood and reducing the stickiness of blood cells. These two actions minimize the leading causes of stroke and heart attack: blood clots (8).
Breaking dead material down small enough that it can immediately pass into the bowel. (8).

Cleansing the FC receptors on the white blood cells, improving their function and availability to fight off infection. (9).
And here we come to the only warning we have to give concerning the use of Vitalzym or any other systemic enzyme - don't use the product if you ar a hemophiliac or are on prescription blood thinners like coumadin, heparin and plavix. The enzymes cause the drugs to work better, so there is the possibility of thinning the blood too much.

Immune System Modulating Enzymes are adaptogenic, seeking to restore a steady state to the body. (9). When the immune system is running low, we become susceptible to infectious disease. When it's cranked up too high, then the system creates antibodies that attack it's own tissues, as are seen in the autoimmune diseases of MS, Rheumatoid Arthritis, and Lupus. Here the Vitalzym will tone down immune function and eat away at the antibodies the immune system is making to attack its bodies own tissue. When the immune system is run down too low, the enzymes increase immune response, producing more Natural Killer cells, and improving the efficiency of the white blood cells, all leading to improved immunity.

Virus Fighting Viruses harm us by replicating in our bodies. To do this, a virus must bond itself to the DNA in our cells through the medium of its exterior protein cell wall. Anything that disrupts that cell wall inhibits the ability of viral replication by rendering individual viruses inert. (10, 11). Systemic enzymes can tell the difference between the proteins that are supposed to be in your body and those that are foreign or not supposed to be there (again the enzyme lock and key mechanism). Vitalzym has the strongest protein eating effect of any enzyme due to its Serrapeptase content and can be of help in combating viruses.

1) Carroll A., R.: Clinical examination of an enzymatic anti-inflammatory agent in emergency surgery. Arztl. Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double blind, randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment of breast engorgement with Serrapeptase: a randomized double blind controlled trial. Singapore Med J. 1989:30(I):48-54.
4) Celebrex article. Wall Street Journal. 19 April 1999.
5) No author listed: Regular Use of Pain Relievers Can Have Dangerous Results. Kaleidoscope Interactive News, American Medical Association media briefing. July 24, 1997.
6) Enzymes - A Drug of the Future, Prof. Heinrich Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regressing of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866, 1982.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic enzymes for modifying blood rheology. Klin Wschr. 65 (1987), 994.
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory capacity of proteases in immune complex decomposition and formation. First International symposium on combination therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using proteolytic enzymes. Der Informierte Arzt. 2 (1974), 424-429.


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